DIMD may involve ANY high-energy system. Warning patterns include:
- Tendon rupture (especially spontaneous or minimal trauma)
- Progressive neuropathy
- New autonomic symptoms
- Postural intolerance
- Joint, tendon, muscle pain
- Muscle spasms
- Heat intolerance
- Vision or hearing changes
- Exercise intolerance
- Severe fatigue unresponsive to rest
- Insomnia
- Gait instability
- Cognitive slowing
- GI disturbances
- Psychological and neuropsychiatric dysfunction (anxiety, depression, panic, emotional lability, derealization)*
- Multi-system symptom overlap without a unifying diagnosis
- Symptoms beginning months to years after medication exposure
*Psychological and neuropsychiatric symptoms in this context are not “primary mental illness.” They often reflect impaired cellular energy metabolism within the central nervous system, driven by mitochondrial dysfunction.
DIMD 